DNA Binding Motif

						

			
Accessions: GCM1_MAX_2_3_4_5 (HumanTF2 1.0)

			
Names: GCM1_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 28
Consensus: rgCACGTGsyyrvkggssrTGCGGGTrs
Weblogo: 
PSSM: P0      A      C      G      T
01    584    399    614    174      r
02    364    335    661    410      g
03      0   1770      0     11      C
04   1770     35     42      5      A
05      0   1770     15     59      C
06     43      0   1770      1      G
07      0     73      6   1770      T
08     17      0   1770     18      G
09    257    648    487    378      s
10    247    460    398    664      y
11    248    471    405    645      y
12    490    344    537    398      r
13    484    483    581    222      v
14    287    329    688    465      k
15    375    336    796    263      g
16    288    233    834    415      g
17    295    479    568    428      s
18    291    483    615    381      s
19   1178    225    591     54      r
20     67    108     79   1770      T
21    335     31   1770      3      G
22    104   1770    173    120      C
23    104      7   1770    373      G
24      0      5   1770     16      G
25      0     12   1770      0      G
26     53    383     37   1387      T
27   1071    178    699    211      r
28    175    622    651    322      s
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
MAX_TF2 (Helix-loop-helix DNA-binding domain)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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