DNA Binding Motif

						

			
Accessions: 3ikt_AB (3D-footprint 20231221)

			
Names: Redox-sensing transcriptional repressor rex
Organisms: strain HB27 / ATCC BAA-163 / DSM 7039, Thermus thermophilus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of a Rex-family repressor/DNA/NAD+ complex from Thermus aquaticus
Length: 18
Consensus: TGTGAnnnnnnTCACAGC
Weblogo: 
PSSM: P0      A      C      G      T
01      6      3      3     84      T
02      0      0     96      0      G
03      6      3      3     84      T
04      0      0     96      0      G
05     87      3      3      3      A
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12      3      7      3     83      T
13      0     96      0      0      C
14     96      0      0      0      A
15      0     96      0      0      C
16     84      6      3      3      A
17      3      3     81      9      G
18      8     70     11      7      C
Type: Heterodimer
Binding TFs: 3ikt_A (CoA binding domain, Putative DNA-binding protein N-terminus)
3ikt_B (CoA binding domain, Putative DNA-binding protein N-terminus)
Binding Sites: 3ikt_C / 3ikt_D
			
Publications: McLaughlin K.J, Strain-Damerell C.M, Xie K, Brekasis D, Soares A.S, Paget M.S, Kielkopf C.L. Structural basis for NADH/NAD+ redox sensing by a Rex family repressor. Molecular cell 38:563-75 (2010). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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