DNA Binding Motif

						

			
Accessions: MA1148.1 (JASPAR 2024)

			
Names: PPARA::RXRA
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: SMiLE-seq
Length: 18
Consensus: awgtrGGtcAaAGGTcAt
Weblogo: 
PSSM: P0      A      C      G      T
01    548    140    108    204      a
02    431     73     60    437      w
03    247    211    332    210      g
04     61     94    238    608      t
05    492     95    370     42      r
06     68     19    843     71      G
07     80     15    856     49      G
08     42    157    245    556      t
09    131    445    201    223      c
10    887     16     67     30      A
11    669     24    208     99      a
12    807     25    143     25      A
13    111     16    862     11      G
14     18     14    784    184      G
15     17     49    115    818      T
16     90    598    146    166      c
17    689     37    230     43      A
18    222    237    243    298      t
Type: Heterodimer
Binding TFs: P19793 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains), Nuclear/hormone receptor activator site AF-1)
Q07869 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
P19793
Q07869
			
Publications: Bardot O, Aldridge TC, Latruffe N, Green S. PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene. Biochem Biophys Res Commun 192:37-45 (1993). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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