DNA Binding Motif

						

			
Accessions: 5v3g_A (3D-footprint 20231221)

			
Names: PR domain zinc finger protein 9
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: PRDM9-allele-C ZnF8-13
Length: 20
Consensus: GGGnAACGCTCACTGGGGTC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      0      0     96      0      G
03      0      0     96      0      G
04     24     24     24     24      n
05     84      4      4      4      A
06     96      0      0      0      A
07      0     96      0      0      C
08      0      0     96      0      G
09      0     91      1      4      C
10      0      0      0     96      T
11      4     77     11      4      C
12     96      0      0      0      A
13     10     73      4      9      C
14      1      4      0     91      T
15      0      0     96      0      G
16      0      0     96      0      G
17      0      0     96      0      G
18      0      0     96      0      G
19     10      9      9     68      T
20      6     77      4      9      C
Binding TFs: 5v3g_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Binding Sites: 5v3g_B
5v3g_C
			
Publications: Patel A, Zhang X, Blumenthal RM, Cheng X. Structural basis of human PR/SET domain 9 (PRDM9) allele C-specific recognition of its cognate DNA sequence. J Biol Chem 292:15994-16002 (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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