DNA Binding Motif

Accessions: UP00008A_2 (UniPROBE 20160601)
Names: Homeobox protein SIX6, Optic homeobox 2, Optx2, Sine oculis homeobox homolog 6, sine oculis-related homeobox 6 homolog (Drosophila), Six6, Six9, Six9 protein
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: mwbskATATATmcryyt
Weblogo:
PSSM: P0 A C G T
01 0.33 0.27 0.21 0.18 m
02 0.27 0.17 0.20 0.35 w
03 0.14 0.28 0.31 0.26 b
04 0.11 0.31 0.47 0.10 s
05 0.03 0.07 0.49 0.42 k
06 0.80 0.06 0.13 0.01 A
07 0.05 0.06 0.01 0.88 T
08 0.90 0.03 0.04 0.03 A
09 0.01 0.02 0.04 0.93 T
10 0.92 0.05 0.01 0.01 A
11 0.02 0.15 0.04 0.80 T
12 0.44 0.49 0.03 0.04 m
13 0.09 0.63 0.12 0.16 c
14 0.33 0.18 0.35 0.14 r
15 0.19 0.33 0.16 0.32 y
16 0.24 0.36 0.13 0.27 y
17 0.15 0.13 0.23 0.48 t
Binding TFs: UP00008A (Homeobox domain, Homeobox KN domain)
Binding Sites: AAGATATC
AATGATAC
AGATATCA
AGGTATCA
AGTATCAT
AGTGATAC
ATGATACC
ATGATATC
ATTGATAC
CTGATATC
GATACCCC
GATATATC
GATATCAA
GATATCAC
GATATCCC
GGATATCA
GGTATCAA
GGTATCAC
TGATATCA
GATATCGC
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.