DNA Binding Motif

						

			
Accessions: E2F1_ELK1_2_3 (HumanTF2 1.0)

			
Names: E2F1_ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: sGCGcsywdkkkrrrsCGGAAGT
Weblogo: 
PSSM: P0      A      C      G      T
01    154    554    604    130      s
02     42     67   1158     54      G
03     22   1158    103     80      C
04     50     71   1158     79      G
05     91   1158    306    189      c
06     57    366    537    198      s
07    269    398    182    309      y
08    396    147    260    355      w
09    307    215    295    342      d
10    238    253    352    315      k
11    257    231    350    320      k
12    184    284    378    312      k
13    309    221    391    237      r
14    292    180    407    280      r
15    460     71    442    185      r
16    160    568    312    118      s
17    144   1158     68      7      C
18      0     11   1158     13      G
19     13      7   1158     21      G
20   1158     27     38     15      A
21   1158     50     31    238      A
22    198    152   1158     41      G
23     52    197    115    794      T
Type: Heterodimer
Binding TFs: E2F1_TF1 (E2F/DP family winged-helix DNA-binding domain)
ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
ELK1_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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