DNA Binding Motif

						

			
Accessions: E2F1_ELK1_1 (HumanTF2 1.0)

			
Names: E2F1_ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: sGCGssyrAmCGGAAGt
Weblogo: 
PSSM: P0      A      C      G      T
01    243    553    831     47      s
02     27     85   1384     24      G
03     26   1384     45     63      C
04     64     25   1384     54      G
05     72   1384    653    113      s
06     10    577    642    155      s
07    194    592    188    410      y
08    615     87    367    316      r
09    982     19     89    295      A
10    710    374     84    217      m
11     77   1384     57     36      C
12     28      4   1384     15      G
13     11     21   1384     42      G
14   1384     25     40     57      A
15   1384     75     43    326      A
16    245    214   1384     35      G
17     62    331    198    793      t
Type: Heterodimer
Binding TFs: E2F1_TF1 (E2F/DP family winged-helix DNA-binding domain)
ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
ELK1_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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