DNA Binding Motif

						

			
Accessions: GCM1_NHLH1_1 (HumanTF2 1.0)

			
Names: GCM1_NHLH1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: gCAGCTGykwsmsbrtGcgGG
Weblogo: 
PSSM: P0      A      C      G      T
01      7     24    106     40      g
02     11    178     30     11      C
03    178     16      0      5      A
04     12     27    178      8      G
05     16    178      8     11      C
06     12      3      7    178      T
07      3      0    178      0      G
08     25     66     35     51      y
09     19      9    105     45      k
10     50     19     29     80      w
11     17     72     49     40      s
12     46     63     27     41      m
13     42     80     51      5      s
14     24     53     55     45      b
15     77     25     67      9      r
16     32     12     44    178      t
17     37     12    141      0      G
18     20    178     33     61      c
19     33      8    178     44      g
20      7     17    178      2      G
21      0      3    178      0      G
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
NHLH1_TF2 (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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