DNA Binding Motif

						

			
Accessions: HOXD12_HOXA3_2 (HumanTF2 1.0)

			
Names: HOXD12_HOXA3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: yTAAtyrssTmrTAAAm
Weblogo: 
PSSM: P0      A      C      G      T
01    414    687    315    690      y
02    372    259    213   2106      T
03   2106    180    212    415      A
04   2106     59     57    314      A
05    229    488    513   2106      t
06    409    611    512    574      y
07   1070    251   1036    289      r
08    346   1282    824    266      s
09    514    540   1040     13      s
10    154    441     69   1665      T
11    728   1379    295    413      m
12   1212    100    894     81      r
13     24      0     66   2106      T
14   2106      0      0    327      A
15   2106      6      0    231      A
16   2106    180      0    284      A
17    723    617    336    431      m
Type: Heterodimer
Binding TFs: HOXD12_TF1 (Homeobox domain)
HOXA3_TF1 / HOXA3_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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