DNA Binding Motif

						

			
Accessions: HOXB2_SPDEF (HumanTF2 1.0)

			
Names: HOXB2_SPDEF
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: AmCCGGATgyrsgymATTA
Weblogo: 
PSSM: P0      A      C      G      T
01    359      0     18     44      A
02    104    219     34      3      m
03     20    359     62      7      C
04     76    359      5      5      C
05      0      0    359      1      G
06      2      0    359      5      G
07    359      0      8      5      A
08    115      4      0    359      T
09     78     53    221      7      g
10      0    143      3    220      y
11    162     29    121     47      r
12     49    157    110     43      s
13     70     55    167     69      g
14     59     92      5    203      y
15    197    163     31     25      m
16    359     18     42     15      A
17      0      2      4    359      T
18     14     54     20    359      T
19    359      8     28     41      A
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
SPDEF_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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