DNA Binding Motif

Accessions: UP00367A_1 (UniPROBE 20160601)
Names: hlh-23, MXL-3
Organisms: Caenorhabditis elegans
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: yrdamCACGTGktymr
Weblogo:
PSSM: P0 A C G T
01 0.18 0.32 0.20 0.30 y
02 0.29 0.20 0.29 0.22 r
03 0.26 0.14 0.30 0.29 d
04 0.67 0.09 0.17 0.07 a
05 0.28 0.61 0.10 0.02 m
06 0.04 0.96 0 0 C
07 0.97 0 0.01 0.01 A
08 0 0.95 0 0.04 C
09 0.04 0 0.95 0 G
10 0.01 0.01 0 0.97 T
11 0 0 0.96 0.04 G
12 0.02 0.10 0.61 0.28 k
13 0.14 0.22 0.09 0.55 t
14 0.14 0.39 0.15 0.32 y
15 0.26 0.28 0.22 0.25 m
16 0.32 0.11 0.36 0.22 r
Binding TFs: UP00367A (Helix-loop-helix DNA-binding domain)
Binding Sites: AACACGTG
ACACGTGC
ACACGTGG
ACACGTGT
ACCACGTG
AGCACGTG
ATCACGTG
CACACGTG
CACGTGAC
CACGTGCA
CACGTGCG
CACGTGGA
CACGTGGC
CACGTGGG
CACGTGTA
CACGTGTC
CCACGTGA
CCACGTGC
CCACGTGG
GCACGTGC
Publications: Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed]

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