DNA Binding Motif

						

			
Accessions: GCM1_MAX_2 (HumanTF2 1.0)

			
Names: GCM1_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 28
Consensus: rgCACGTGkkyvsgggcgrTGCGGGyrs
Weblogo: 
PSSM: P0      A      C      G      T
01    809    363    874    454      r
02    583    521   1165    230      g
03      0   2499      2      9      C
04   2499      0     15     20      A
05      2   2499      0     41      C
06     30      0   2499     18      G
07      4     26      4   2499      T
08     37      0   2499     14      G
09    365    446    947    741      k
10    269    324    684   1222      k
11    493    797    236    973      y
12    774    661    709    355      v
13    479   1022    756    243      s
14    582    215   1281    421      g
15    536    588    921    455      g
16    515    187   1625    172      g
17    406   1123    461    509      c
18    623    338   1017    522      g
19   1725    186    775     36      r
20     96     67     40   2499      T
21    387     58   2499      0      G
22    276   2499    190    108      C
23    281     26   2499    545      G
24      0      0   2499      5      G
25      0      4   2499      0      G
26     70   1420     80   1079      y
27   1374    452   1125    359      r
28    450    704    790    557      s
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
MAX_TF2 (Helix-loop-helix DNA-binding domain)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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