DNA Binding Motif

						

			
Accessions: ZNF597_2 (HT-SELEX2 May2017), UN0208.1 (JASPAR 2024)

			
Names: ZNF597
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 14
Consensus: sgcCGCCATyTTGd
Weblogo: 
PSSM: P0      A      C      G      T
01   6300   8204  12907   5359      s
02   5211   1704  24627   9049      g
03   8177  23630   4004   2998      c
04   1640  28394   6060     60      C
05    152      0  32686    168      G
06     82  32769      0     11      C
07      0  32766      0     14      C
08  32763     28     12      6      A
09     46     72     14  32758      T
10   2100  10574   1579  21229      y
11    136     40     53  32726      T
12     76     78     43  32765      T
13   2203    796  31198   2415      G
14   8829   5083   9358   9501      d
Type: Heterodimer
Binding TFs: Q96LX8 / ZNF597 (Zinc finger, C2H2 type, KRAB box, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Q96LX8
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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