DNA Binding Motif
| Accessions: | MA1110.1 (JASPAR 2024) |
| Names: | NR1H4 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | ChIP-seq |
| Length: | 11 |
| Consensus: | tcAATGACCyh |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 76 83 117 229 t 02 68 240 87 110 c 03 461 10 12 22 A 04 413 28 36 28 A 05 3 15 6 481 T 06 24 7 462 12 G 07 455 22 14 14 A 08 26 468 0 11 C 09 12 476 6 11 C 10 72 135 81 217 y 11 135 131 105 134 h |
| Type: | Heterodimer |
| Binding TFs: | Q96RI1 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains)) Q96RI1 |
| Binding Sites: | MA1110.1.1 MA1110.1.10 MA1110.1.11 MA1110.1.12 MA1110.1.13 MA1110.1.14 MA1110.1.15 MA1110.1.16 MA1110.1.17 MA1110.1.18 MA1110.1.19 MA1110.1.2 MA1110.1.20 MA1110.1.3 MA1110.1.4 MA1110.1.5 MA1110.1.6 MA1110.1.7 MA1110.1.8 MA1110.1.9 |
| Publications: | Hoeke MO, Heegsma J, Hoekstra M, Moshage H, Faber KN. Human FXR regulates SHP expression through direct binding to an LRH-1 binding site, independent of an IR-1 and LRH-1. PLoS One : (2014). [Pubmed] |
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