DNA Binding Motif

						

			
Accessions: TEAD4_DLX3_2_3 (HumanTF2 1.0)

			
Names: TEAD4_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rCATwCCdysstAAtkr
Weblogo: 
PSSM: P0      A      C      G      T
01    671     49    672     34      r
02    352   1343    199      0      C
03   1343      0    144      0      A
04     15      3      5   1343      T
05   1088      2    340   1343      w
06     19   1343     94     43      C
07      6   1343     26    395      C
08    405    204    367    367      d
09    273    432    298    340      y
10    326    371    375    271      s
11    317    367    391    268      s
12    349    243     81   1343      t
13   1343     53    437     43      A
14   1343      3     15      5      A
15    213    312    342   1343      t
16    451    530    622    721      k
17    615    325    728    252      r
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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