DNA Binding Motif

Accessions: TEAD4_ALX4_1 (HumanTF2 1.0)
Names: TEAD4_ALX4
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: GGAATGytAamytAATTa
Weblogo:
PSSM: P0 A C G T
01 30 9 155 11 G
02 3 23 155 6 G
03 155 11 3 43 A
04 155 0 1 4 A
05 0 3 14 155 T
06 12 17 155 13 G
07 24 41 20 71 y
08 12 38 29 76 t
09 110 7 11 27 A
10 100 33 13 8 a
11 48 48 26 33 m
12 5 88 5 67 y
13 35 32 10 155 t
14 155 31 8 9 A
15 155 3 0 0 A
16 0 4 7 155 T
17 23 33 5 155 T
18 155 15 40 33 a
Type: Heterodimer
Binding TFs: ALX4_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
ALX4_TF1 (Homeobox domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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