DNA Binding Motif

						

			
Accessions: HOXB2_ETV7_2_3 (HumanTF2 1.0)

			
Names: HOXB2_ETV7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: rsmGGAAGTrrrgymrTYAg
Weblogo: 
PSSM: P0      A      C      G      T
01     80     49     85     13      r
02     45    149     77      9      s
03    122    226     49     13      m
04      3      0    226      7      G
05      0      0    226     12      G
06    226     34      0      7      A
07    226     49      0      7      A
08     48      3    178      0      G
09     39     33      0    167      T
10    108      0    100     32      r
11     76     46     72     31      r
12     70     26    132      0      r
13     53     50    113     10      g
14      0     62     16    152      y
15    111    115      0     23      m
16    226     24    138     29      r
17      7      0      9    226      T
18      0     87      3    226      Y
19    226      5     43      7      A
20     40     47    121     17      g
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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