DNA Binding Motif

						

			
Accessions: ETV2_RFX5_2 (HumanTF2 1.0)

			
Names: ETV2_RFX5
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: rCCGGAArymvCmTAGCAACs
Weblogo: 
PSSM: P0      A      C      G      T
01    384    162    349    273      r
02     85   1149     38      1      C
03     50   1165      8      0      C
04      0      0   1168      0      G
05      0      0   1168      2      G
06   1168      0      1      0      A
07   1101     30      0    187      A
08    366    104    926      4      r
09     47    601     94    566      y
10    366    339    173    290      m
11    308    344    493     23      v
12     54   1076    181     92      C
13    424    375    264    104      m
14     42    207     18   1073      T
15   1062     53    338      5      A
16     70     13   1168      2      G
17     34   1168      4     41      C
18   1168     19     54     12      A
19   1168      8      7     14      A
20      7   1168      0     14      C
21    190    490    503    127      s
Type: Heterodimer
Binding TFs: RFX5_TF2 (RFX DNA-binding domain, Poxvirus D5 protein-like)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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