DNA Binding Motif

						

			
Accessions: SOX2_DBD_1 (HumanTF 1.0)

			
Names: SOX2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 4; Possible binding to single stranded DNA
Length: 17
Consensus: rAACAATGkyAKTGTTm
Weblogo: 
PSSM: P0      A      C      G      T
01   1331    329   2564    789      r
02   5014     18     92     37      A
03   5014    200     43     15      A
04      0   5014      0     13      C
05   5014      0      0      0      A
06   5014     15      0      0      A
07      0      3      0   5014      T
08    282     11   4132    589      G
09    673    410   2248   1682      k
10    215   1515     14   3269      y
11   5014      4      0      3      A
12      4      5   2321   5014      K
13     87      3      3   5014      T
14      0      3   5014      0      G
15     39      3     49   5014      T
16    127    214    174   5014      T
17   1302   1838   1034    839      m
Binding TFs: SOX2_DBD (HMG (high mobility group) box, Domain of unknown function (DUF1898), SOX transcription factor)
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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