DNA Binding Motif

						

			
Accessions: 5eh2_F (3D-footprint 20231221)

			
Names: Histone-lysine N-methyltransferase PRDM9
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence III
Length: 12
Consensus: mCTCCCTAGCCa
Weblogo: 
PSSM: P0      A      C      G      T
01     31     39     13     13      m
02      1     92      2      1      C
03      3      3      3     87      T
04      4     82      5      5      C
05      1     95      0      0      C
06      2     90      2      2      C
07      0      3      1     92      T
08     71      1     22      2      A
09      3      0     93      0      G
10     12     74      5      5      C
11      0     95      1      0      C
12     57     13     13     13      a
Binding TFs: 5eh2_F (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Binding Sites: 5eh2_C
5eh2_D
			
Publications: Patel A, Horton JR, Wilson GG, Zhang X, Cheng X. Structural basis for human PRDM9 action at recombination hot spots. Genes Dev 30:257-65 (2016). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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