DNA Binding Motif

						

			
Accessions: ETV2_FOXO6 (HumanTF2 1.0), UN0516.1 (JASPAR 2024)

			
Names: ETV2_FOXO6, ETV2::FOXO6
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 13
Consensus: rCCGGAWGTTkwy
Weblogo: 
PSSM: P0      A      C      G      T
01   2389    327   1453    731      r
02    595   3841    743    358      C
03    267   3841     60      0      C
04      1      9   3841      8      G
05      4      1   3841     96      G
06   3841     20      0    173      A
07   1424     51     14   3841      W
08    133      3   3841    106      G
09    206    572    197   3841      T
10    628    336    785   3841      T
11    595    194   1826   2016      k
12   1821    699    638   2020      w
13    158   1575    818   1290      y
Type: Heterodimer
Binding TFs: FOXO6_TF2 (Fork head domain)
ETV2_TF1 (Ets-domain)
Q3KNT2 (Ets-domain)
Q3KNT2
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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