DNA Binding Motif

Accessions: HOXD12_EOMES_1 (HumanTF2 1.0)
Names: HOXD12_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 30
Consensus: agGyGyGAmrmwamatTmACACCTCrTaAa
Weblogo:
PSSM: P0 A C G T
01 2679 650 543 342 a
02 850 781 2582 870 g
03 41 192 2728 211 G
04 9 1800 0 964 y
05 5 19 2770 0 G
06 940 1099 220 1630 y
07 60 770 2637 289 G
08 2753 4 574 26 A
09 1035 897 246 589 m
10 922 409 1102 335 r
11 1139 704 615 309 m
12 786 403 477 1101 w
13 1659 307 196 605 a
14 693 1047 430 598 m
15 1474 460 240 594 a
16 204 658 684 1222 t
17 437 206 149 1975 T
18 732 1585 228 223 m
19 1965 50 505 247 A
20 26 2648 14 80 C
21 2393 22 306 47 A
22 247 2297 178 45 C
23 157 2289 286 35 C
24 26 750 7 2306 T
25 463 2676 442 76 C
26 1024 206 1389 353 r
27 71 0 53 2765 T
28 1942 608 73 713 a
29 2699 88 232 248 A
30 2422 234 341 588 a
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
HOXD12_TF1 (Homeobox domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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