DNA Binding Motif

						

			
Accessions: 5h3r_AB (3D-footprint 20231221)

			
Names: Multiple antibiotic resistance protein MarR
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of mutant MarR C80S from E.coli complexed with operator DNA
Length: 18
Consensus: TnnTTGCCnGGGCAAnnT
Weblogo: 
PSSM: P0      A      C      G      T
01      4      9      4     79      T
02     24     24     24     24      n
03     24     24     24     24      n
04      4      5      4     83      T
05      4      8      5     79      T
06      0      0     96      0      G
07      0     96      0      0      C
08      4     84      4      4      C
09     24     24     24     24      n
10      1      8     79      8      G
11      0      0     96      0      G
12      0      0     96      0      G
13      0     96      0      0      C
14     84      4      4      4      A
15     96      0      0      0      A
16     24     24     24     24      n
17     24     24     24     24      n
18      5      4      4     83      T
Type: Heterodimer
Binding TFs: 5h3r_A (MarR family, MarR family, Winged helix DNA-binding domain)
5h3r_B (MarR family, MarR family, Winged helix DNA-binding domain)
Binding Sites: 5h3r_C
5h3r_D
			
Publications: Zhu R, Hao Z, Lou H, Song Y, Zhao J, Chen Y, Zhu J, Chen PR. Structural characterization of the DNA-binding mechanism underlying the copper(II)-sensing MarR transcriptional regulator. J Biol Inorg Chem 22:685-693 (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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