DNA Binding Motif

						

			
Accessions: EN1_methyl_2 (HT-SELEX2 May2017)

			
Names: EN1
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Length: 8
Consensus: vTCrTTAs
Weblogo: 
PSSM: P0      A      C      G      T
01    691    741    650      0      v
02    463      0    403   2080      T
03    271   2080      0     75      C
04   1663     36   2080      0      r
05      0    128      0   2080      T
06    388    327    156   2080      T
07   2080      0     77      0      A
08    420    528    693    438      s
Binding TFs: EN1 (Homeobox domain, Engrailed homeobox C-terminal signature domain)
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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