DNA Binding Motif

						

			
Accessions: 5v0l_AB (3D-footprint 20231221)

			
Names: Aryl hydrocarbon receptor nuclear translocator
Organisms: Homo sapiens, Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the AHR-ARNT heterodimer in complex with the DRE
Length: 5
Consensus: wcAGC
Weblogo: 
PSSM: P0      A      C      G      T
01     24     16     16     40      w
02     16     48     16     16      c
03     72      8     16      0      A
04      0      0     96      0      G
05      0     96      0      0      C
Type: Heterodimer
Binding TFs: 5v0l_A (Helix-loop-helix DNA-binding domain, PAS fold)
5v0l_B (Helix-loop-helix DNA-binding domain, PAS fold)
Binding Sites: 5v0l_C
5v0l_D
			
Publications: Seok SH, Lee W, Jiang L, Molugu K, Zheng A, Li Y, Park S, Bradfield CA, Xing Y. Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proc Natl Acad Sci U S A 114:5431-5436 (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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