DNA Binding Motif

						

			
Accessions: TEAD4_MAX_1 (HumanTF2 1.0)

			
Names: TEAD4_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: GGwATGyrCACGTG
Weblogo: 
PSSM: P0      A      C      G      T
01    297     35   1093     83      G
02    147    371   1389     44      G
03   1389    221     88    971      w
04   1389     31     11     73      A
05      6    158     12   1389      T
06     73     22   1389    321      G
07    166    699    142    690      y
08    366    252    765      7      r
09      0   1377      8      8      C
10   1389     19      0      7      A
11     20   1389      7     40      C
12     74     41   1389     16      G
13      3     44      6   1389      T
14     20     29   1389     13      G
Type: Heterodimer
Binding TFs: MAX_TF2 (Helix-loop-helix DNA-binding domain)
TEAD4_TF1 (TEA/ATTS domain family)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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