DNA Binding Motif

Accessions: GCM1_FIGLA_2_3 (HumanTF2 1.0)
Names: GCM1_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: CAssTGkkgsgkkggrTGcGGG
Weblogo:
PSSM: P0 A C G T
01 22 1446 69 59 C
02 1446 59 124 90 A
03 16 478 968 37 s
04 10 563 883 11 s
05 45 65 70 1446 T
06 20 6 1446 51 G
07 153 277 534 482 k
08 313 255 462 417 k
09 312 281 561 292 g
10 219 381 499 347 s
11 287 264 590 305 g
12 352 275 455 364 k
13 315 302 452 377 k
14 296 294 506 351 g
15 250 355 526 316 g
16 652 180 560 54 r
17 157 117 175 1446 T
18 481 89 1446 10 G
19 336 1446 462 400 c
20 178 75 1446 405 G
21 11 52 1446 84 G
22 7 2 1446 31 G
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
GCM1_TF1 (GCM motif protein)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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