DNA Binding Motif
| Accessions: | NR2C1_3 (HT-SELEX2 May2017), MA1535.1 (JASPAR 2024) |
| Names: | NR2C1 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1, JASPAR 2024 2 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | HT-SELEX |
| Length: | 9 |
| Consensus: | mrrGGTCAy |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 2552 2848 1997 2225 m 02 4035 1225 5587 1316 r 03 4866 227 4756 55 r 04 0 0 9622 297 G 05 0 0 9622 0 G 06 0 0 271 9622 T 07 0 9622 321 0 C 08 9622 0 1716 0 A 09 2298 2786 2039 2499 y |
| Type: | Heterodimer |
| Binding TFs: | P13056 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains)) NR2C1 (Zinc finger, C4 type (two domains)) P13056 |
| Publications: | Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] Weirauch MT, Cote A, Norel R, Annala M, Zhao Y, Riley TR, Saez-Rodriguez J, Cokelaer T, Vedenko A, Talukder S; DREAM5 Consortium, Bussemaker HJ, Morris QD, Bulyk ML, Stolovitzky G, Hughes TR. Evaluation of methods for modeling transcription factor sequence specificity. Nat Biotechnol 31:126-34 (2013). [Pubmed] |
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