DNA Binding Motif

						

			
Accessions: 4iqr_AB (3D-footprint 20231221)

			
Names: Hepatocyte nuclear factor 4-alpha
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Multi-Domain Organization of the HNF4alpha Nuclear Receptor Complex on DNA
Length: 11
Consensus: GACCtnTKaCC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02     72      6      6     12      A
03      4     89      3      0      C
04      0     96      0      0      C
05     12     13     17     54      t
06     24     24     24     24      n
07      3      3      3     87      T
08      0      3     25     68      K
09     65     11     10     10      a
10      0     96      0      0      C
11      0     96      0      0      C
Type: Heterodimer
Binding TFs: 4iqr_A (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
4iqr_B (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
Binding Sites: 4iqr_C
4iqr_D
			
Publications: Chandra V, Huang P, Potluri N, Wu D, Kim Y, Rastinejad F. Multidomain integration in the structure of the HNF-4α nuclear receptor complex. Nature 495:394-8 (2013). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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