DNA Binding Motif

						

			
Accessions: 1a02_FJN (3D-footprint 20231221)

			
Names: AP-1 FRAGMENT FOS
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA
Length: 15
Consensus: GGAananwTGnyTCA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      0      0     96      0      G
03     96      0      0      0      A
04     61      7     21      7      a
05     24     24     24     24      n
06     56     17      6     17      a
07     24     24     24     24      n
08     24     14      7     51      w
09      0      3      1     92      T
10      0      0     96      0      G
11     24     24     24     24      n
12      3     32      8     53      y
13      0      0      0     96      T
14      0     96      0      0      C
15     96      0      0      0      A
Type: Heterodimer
Binding TFs: 1a02_F (bZIP transcription factor, Basic region leucine zipper)
1a02_J (bZIP transcription factor, Basic region leucine zipper)
1a02_N (Rel homology domain (RHD), IPT/TIG domain)
Binding Sites: 1a02_A
1a02_B
			
Publications: Chen L., Glover J. N. M., Hogan P. G., Rao A., Harrison S. C. Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA.. Nature 392:42-48 (1998). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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