DNA Binding Motif

Accessions: FOXO1_ETV4_1 (HumanTF2 1.0)
Names: FOXO1_ETV4
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: rccGGAwGTkkw
Weblogo:
PSSM: P0 A C G T
01 236 39 151 72 r
02 90 387 152 44 c
03 135 387 58 7 c
04 1 0 387 9 G
05 0 1 387 40 G
06 387 0 0 9 A
07 152 0 0 236 w
08 69 14 387 0 G
09 22 67 34 387 T
10 66 25 141 246 k
11 127 43 175 212 k
12 120 62 90 114 w
Type: Heterodimer
Binding TFs: ETV4_TF2 (Ets-domain)
FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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