DNA Binding Motif

Accessions: MA1640.1 (JASPAR 2024)
Names: MEIS2, MEIS2(var.2)
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 15
Consensus: raaTGATTTATgryy
Weblogo:
PSSM: P0 A C G T
01 6212 3311 5768 4882 r
02 6445 4041 4683 5004 a
03 9929 2365 3896 3983 a
04 3885 468 1400 14420 T
05 1478 302 17326 1067 G
06 19361 207 224 381 A
07 576 268 499 18830 T
08 712 201 278 18982 T
09 1623 582 1801 16167 T
10 19344 177 495 157 A
11 474 1053 502 18144 T
12 2623 1089 12862 3599 g
13 5762 1609 8199 4603 r
14 3882 6518 4176 5597 y
15 4556 5248 3361 7008 y
Type: Heterodimer
Binding TFs: O14770 (Homeobox domain, Homeobox KN domain)
O14770
Binding Sites: MA1640.1.1
MA1640.1.10 / MA1640.1.7
MA1640.1.11
MA1640.1.12 / MA1640.1.8
MA1640.1.13 / MA1640.1.9
MA1640.1.10 / MA1640.1.14
MA1640.1.11 / MA1640.1.15
MA1640.1.12 / MA1640.1.16
MA1640.1.13 / MA1640.1.17
MA1640.1.14 / MA1640.1.18
MA1640.1.15 / MA1640.1.19
MA1640.1.1 / MA1640.1.2
MA1640.1.16 / MA1640.1.20
MA1640.1.2 / MA1640.1.3
MA1640.1.4
MA1640.1.5
MA1640.1.6
MA1640.1.7
MA1640.1.8
MA1640.1.5 / MA1640.1.9
MA1640.1.17
MA1640.1.18
MA1640.1.19
MA1640.1.20
MA1640.1.3
MA1640.1.6
Publications: Penkov D, Mateos San Martín D, Fernandez-Díaz LC, Rosselló CA, Torroja C, Sánchez-Cabo F, Warnatz HJ, Sultan M, Yaspo ML, Gabrieli A, Tkachuk V, Brendolan A, Blasi F, Torres M. Analysis of the DNA-binding profile and function of TALE homeoproteins reveals their specialization and specific interactions with Hox genes/proteins. Cell Rep 3:1321-33 (2013). [Pubmed]

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