DNA Binding Motif

						

			
Accessions: TEAD4_ELK3 (HumanTF2 1.0)

			
Names: TEAD4_ELK3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: ACCGGAAGTdawmrMATwCy
Weblogo: 
PSSM: P0      A      C      G      T
01    646     10     87     32      A
02    119    775    106     40      C
03     46    775     12     30      C
04     27     13    775     33      G
05     21      8    775      0      G
06    775      4      0      9      A
07    775     23      0     64      A
08     92     21    651     11      G
09     37    106      8    624      T
10    235     63    263    214      d
11    284    163    190    139      a
12    261    170    123    221      w
13    196    282    133    164      m
14    271     25    468     10      r
15    225    550     31      1      M
16    775     27     22     21      A
17      3      6      0    775      T
18    362      0     74    414      w
19    169    775     61     37      C
20    107    775     51    553      y
Type: Heterodimer
Binding TFs: ELK3_TF2 (Ets-domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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