DNA Binding Motif

						

			
Accessions: GCM1_MAX_1 (HumanTF2 1.0)

			
Names: GCM1_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: rbCACGTGsrTGckGGyr
Weblogo: 
PSSM: P0      A      C      G      T
01   1109    604   1768    353      r
02    380   1183   1258   1014      b
03     22   3835    101     46      C
04   3835     11     98     53      A
05     38   3835     79    104      C
06     47      4   3835      0      G
07     42    101     54   3835      T
08     34      0   3835      0      G
09    246   1246   1822    520      s
10   1749    364    992    730      r
11    145    312    116   3263      T
12    634    202   3835     46      G
13    887   3835    965    690      c
14    375    127   3835   1568      k
15     70    174   3835    501      G
16     41    115   3835    284      G
17    376   1490    271   2345      y
18   1330    402   1430    674      r
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
MAX_TF2 (Helix-loop-helix DNA-binding domain)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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