DNA Binding Motif

						

			
Accessions: ERF_DLX2_1 (HumanTF2 1.0)

			
Names: ERF_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: rsmGGAwrtsrvymaTTA
Weblogo: 
PSSM: P0      A      C      G      T
01    279     55    152    110      r
02    106    230    201     55      s
03    281    431     10      0      m
04      0      1    431      0      G
05      6      1    431      8      G
06    431      9      2      0      A
07    431     44      0    214      w
08    169     39    184     39      r
09     76     76     26    252      t
10     84    123    162     61      s
11    117     89    210     15      r
12    120    149    125     37      v
13     41    225     55    205      y
14    267    164     52     17      m
15    431    155     42     57      a
16     11     32     41    431      T
17     28     59      5    431      T
18    431     53     60     84      A
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
ERF_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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