DNA Binding Motif

						

			
Accessions: POU2F1_GSC2_1 (HumanTF2 1.0), POU2F1_GSC2_2 (HumanTF2 1.0)

			
Names: POU2F1_GSC2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: mrgATTAwdyATkCawaww
Weblogo: 
PSSM: P0      A      C      G      T
01   2191   2161   1867   1372      m
02   2578   1278   2916    819      r
03   2976   1729   7591   2455      g
04   7591   2201    407    800      A
05    165    245     86   7591      T
06    565    797    250   7591      T
07   7591     99    482    948      A
08   2201   1422   1671   2297      w
09   2101   1114   2326   2050      d
10    606   1920    370   4695      y
11   7591     47    133    322      A
12    739    575    567   7591      T
13    962    161   7591   3982      k
14    470   7591    525   2017      C
15   7591    882   1766   2434      a
16   4433   1514   1825   3158      w
17   3502    996   1436   1657      a
18   2024   1427   1475   2665      w
19   2166   1764   1659   2002      w
Type: Heterodimer
Binding TFs: GSC2_TF2 (Homeobox domain)
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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