DNA Binding Motif

						

			
Accessions: CUX1_HOXB13 (HumanTF2 1.0), UN0487.1 (JASPAR 2024)

			
Names: CUX1_HOXB13, CUX1::HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 16
Consensus: symrTAAAhATyGATy
Weblogo: 
PSSM: P0      A      C      G      T
01    476   1688    989    107      s
02    169   1209    102   1467      y
03   1159   1518     88    605      m
04   1380     33   1296     37      r
05      0     52     35   2677      T
06   2677     36    173    550      A
07   2677    106     13    246      A
08   2677    101     85    129      A
09    771    891    145    871      h
10   2677      0      0     84      A
11      0      0      0   2677      T
12     18   1745      0    932      y
13      7      8   2677      0      G
14   2677     35     85     65      A
15    157    184      0   2677      T
16    390   1326    196    764      y
Type: Heterodimer
Binding TFs: CUX1_TF1 (Homeobox domain, CUT domain, Homeobox KN domain)
HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
Q92826 (Homeobox domain, Hox protein A13 N terminal)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
Q92826
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.