DNA Binding Motif

						

			
Accessions: UP00179A_1 (UniPROBE 20160601)

			
Names: class 2, Epoc-1, Epoc1, Oct-11, Oct-11a, Oct11, Octamer-binding transcription factor 11, Otf-11, Otf11, POU domain, Pou2f3, Skin, Skin-1a, Skn-1a, Skn-li, transcription factor 3
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: ttkTATGCWAATkara
Weblogo: 
PSSM: P0      A      C      G      T
01   0.16   0.20   0.20   0.44      t
02   0.24   0.22   0.15   0.39      t
03   0.19   0.13   0.40   0.28      k
04   0.09   0.12   0.04   0.75      T
05   0.99      0      0   0.01      A
06      0   0.01      0   0.98      T
07      0      0   0.94   0.06      G
08      0   0.91      0   0.08      C
09   0.74      0      0   0.26      W
10   0.91      0   0.01   0.08      A
11   0.99      0      0   0.01      A
12   0.02      0   0.02   0.96      T
13   0.15   0.16   0.29   0.40      k
14   0.46   0.24   0.11   0.19      a
15   0.29   0.16   0.35   0.19      r
16   0.41   0.24   0.18   0.16      a
Binding TFs: UP00179A (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Binding Sites: AATTAATT
ACTAATTA
ATAATGAG
ATAATTAG
ATGCATAA
ATGCTAAT
ATTAATTA
ATTATGCA
ATTTAAAT
CCTAATTA
CCTCATTA
CTAATTAA
CTAATTAG
CTCATTAA
GCTAATTA
GTTAATTA
TAATTAGA
TATGCAAA
TATGCATA
TATGCTAA
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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