DNA Binding Motif

						

			
Accessions: UP00587E_1 (UniPROBE 20160601)

			
Names: AT591, CMT1D, CMT4E, DKFZp686J1957, E3 SUMO-protein ligase EGR2, Early growth response protein 2, EGR-2, EGR2_R409W_R1, FLJ14547, KROX20, Zinc finger protein Krox-20
Organisms: Homo sapiens
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 22
Consensus: tmwyyytCCCCGCCCythyata
Weblogo: 
PSSM: P0      A      C      G      T
01   0.18   0.08   0.12   0.62      t
02   0.41   0.28   0.16   0.16      m
03   0.35   0.12   0.12   0.41      w
04   0.15   0.31   0.04   0.50      y
05   0.20   0.29   0.11   0.40      y
06   0.20   0.32   0.06   0.42      y
07   0.24   0.19   0.25   0.33      t
08   0.12   0.75   0.06   0.07      C
09   0.06   0.84   0.01   0.09      C
10   0.05   0.94      0   0.01      C
11   0.01   0.98      0   0.01      C
12   0.05      0   0.94   0.02      G
13      0   0.99      0      0      C
14   0.01   0.99   0.01      0      C
15   0.01   0.91      0   0.07      C
16   0.22   0.37   0.03   0.38      y
17   0.22   0.25   0.17   0.37      t
18   0.35   0.34   0.05   0.25      h
19   0.16   0.51   0.05   0.28      y
20   0.50   0.17   0.20   0.13      a
21   0.22   0.11   0.19   0.47      t
22   0.57   0.08   0.15   0.21      a
Binding TFs: UP00587E (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: CCCGCCCC
ACCCGCCC
ACGCCCAT
ACGCCCTA
AGGGCGGA
AGGGCGGG
CCCCGCCC
CCCGCCCA
CCGCCCCA
CCGCCCCG
GGGCGGAA
GGGCGTAC
GGGGCGTA
AAGGGCGG
ACCGCCCT
AGGGCGTA
ATACGCCC
GGGCGTAA
TACGCCCA
TCCGCCCA
			
Publications: Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M, Daly MJ, Vidal M, Hill DE, Bulyk ML. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science 351:1450-4 (2016). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.