DNA Binding Motif

						

			
Accessions: TEAD4_SOX6 (HumanTF2 1.0)

			
Names: TEAD4_SOX6
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: rrACAATrgaawGGwATGy
Weblogo: 
PSSM: P0      A      C      G      T
01    261     77    457    101      r
02    527    119    236     13      r
03    895     24     38     16      A
04     16    895     77     67      C
05    895      0     29     22      A
06    895     29     58     14      A
07     95     62     42    895      T
08    282     70    482     60      r
09    144    147    521     83      g
10    350    154    189    202      a
11    405    159    192    139      a
12    284    187    133    290      w
13    178      0    656     65      G
14     52    110    895     16      G
15    895    134      9    462      w
16    895     18     10     39      A
17      0     55      0    895      T
18      0      0    895     19      G
19     34    421      0    474      y
Type: Heterodimer
Binding TFs: TEAD4_TF1 (TEA/ATTS domain family)
SOX6_TF1 / SOX6_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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