DNA Binding Motif

Accessions: 1le5_EF (3D-footprint 20231221)
Names: Nuclear factor NF-kappa-B p65 subunit
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of a NF-kB heterodimer bound to an IFNb-kB
Length: 10
Consensus: GGGAantTCC
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 0 0 96 0 G
03 0 0 96 0 G
04 96 0 0 0 A
05 54 13 16 13 a
06 24 24 24 24 n
07 13 13 16 54 t
08 0 0 0 96 T
09 0 96 0 0 C
10 0 96 0 0 C
Type: Heterodimer
Binding TFs: 1le5_E (Rel homology domain (RHD))
1le5_F (Rel homology domain (RHD))
Binding Sites: 1le5_G
1le5_H
Publications: Berkowitz B, Huang D.B, Chen-Park F.E, Sigler P.B, Ghosh G. The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site. The Journal of biological chemistry 277:24694-700 (2002). [Pubmed]

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