DNA Binding Motif

						

			
Accessions: TEAD4_DRGX_2 (HumanTF2 1.0), UN0581.1 (JASPAR 2024)

			
Names: TEAD4_DRGX, TEAD4::DRGX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 13
Consensus: GGwATGTTAATtr
Weblogo: 
PSSM: P0      A      C      G      T
01    541     51   2233     97      G
02     84    165   2233     26      G
03   2233    259      8   1078      w
04   2233      3      9      4      A
05      0     87     11   2233      T
06      0     34   2233    306      G
07    121    401    101   2233      T
08    111     73     11   2233      T
09   2233     19    104      0      A
10   2233      1     14      7      A
11     96     68    261   2233      T
12    135    393    645   2233      t
13    854    334   1379    320      r
Type: Heterodimer
Binding TFs: DRGX_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
Q15561 (TEA/ATTS domain family)
Q15561
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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