DNA Binding Motif

Accessions: TEAD4_HOXB13_2_3_4_5_6 (HumanTF2 1.0)
Names: TEAD4_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: stcrTAAAATGy
Weblogo:
PSSM: P0 A C G T
01 72 151 79 2 s
02 28 127 54 304 t
03 52 304 13 108 c
04 120 0 304 32 r
05 10 0 3 304 T
06 304 0 64 60 A
07 304 0 22 28 A
08 304 13 1 42 A
09 304 42 5 26 A
10 5 38 13 304 T
11 13 31 304 28 G
12 4 304 23 164 y
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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