DNA Binding Motif

						

			
Accessions: HOXB2_ETV7_2 (HumanTF2 1.0)

			
Names: HOXB2_ETV7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: rscGGAArtavsymATTAr
Weblogo: 
PSSM: P0      A      C      G      T
01    214    171    233     83      r
02    104    367    333     43      s
03    260    700     72     25      c
04     20      0    700      0      G
05      0      0    700      2      G
06    700     17      0     36      A
07    700     29      2     15      A
08    291     24    409      9      r
09    144     92      0    491      t
10    420     71    154     55      a
11    233    193    212     63      v
12    137    177    295     91      s
13     41    270     90    299      y
14    308    392    105     29      m
15    700     56    161      5      A
16      0      0     16    700      T
17      0      0     23    700      T
18    700      0     17     48      A
19    219    135    301     45      r
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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