DNA Binding Motif

Accessions: 6mg3_AB (3D-footprint 20231221)
Names: CCAAT/enhancer-binding protein beta
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: V285A Mutant of the C-terminal bZIP domain of human C/EBPbeta with 16bp Methylated Oligonucleotide Containing Consensus Recognition Sequence
Length: 10
Consensus: aTTnnnnAAt
Weblogo:
PSSM: P0 A C G T
01 54 13 16 13 a
02 0 0 0 96 T
03 0 0 0 96 T
04 24 24 24 24 n
05 24 24 24 24 n
06 24 24 24 24 n
07 24 24 24 24 n
08 96 0 0 0 A
09 96 0 0 0 A
10 13 13 16 54 t
Type: Heterodimer
Binding TFs: 6mg3_A (bZIP transcription factor, Basic region leucine zipper)
6mg3_B (bZIP transcription factor, Basic region leucine zipper)
Binding Sites: 6mg3_D
6mg3_C
Publications: Yang J, Horton JR, Wang D, Ren R, Li J, Sun D, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for effects of CpA modifications on C/EBPβ binding of DNA. Nucleic Acids Res : (2018). [Pubmed]

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