DNA Binding Motif

						

			
Accessions: 2pue_A (3D-footprint 20231221)

			
Names: PROTEIN (PURINE REPRESSOR )
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES
Length: 8
Consensus: CGCanACg
Weblogo: 
PSSM: P0      A      C      G      T
01      0     96      0      0      C
02      0      0     96      0      G
03      0     96      0      0      C
04     54     13     16     13      a
05     24     24     24     24      n
06     96      0      0      0      A
07      0     96      0      0      C
08     13     13     54     16      g
Binding TFs: 2pue_A (Bacterial regulatory proteins, lacI family, Periplasmic binding proteins and sugar binding domain of LacI family, Periplasmic binding protein-like domain, Periplasmic binding protein domain)
Binding Sites: 2pue_B
			
Publications: Lu F, Schumacher M.A, Arvidson D.N, Haldimann A, Wanner B.L, Zalkin H, Brennan R.G. Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190. Biochemistry 37:971-82 (1998). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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