DNA Binding Motif

Accessions: GCM2_SOX15_2_3 (HumanTF2 1.0)
Names: GCM2_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: ATRcGGGywbraaACAAwr
Weblogo:
PSSM: P0 A C G T
01 242 47 42 24 A
02 51 40 0 284 T
03 77 0 207 4 R
04 43 284 59 72 c
05 12 13 284 43 G
06 0 4 284 8 G
07 0 0 284 4 G
08 17 82 29 156 y
09 133 25 44 81 w
10 58 73 72 81 b
11 97 66 84 37 r
12 203 55 81 86 a
13 144 62 37 41 a
14 284 14 23 55 A
15 2 284 18 32 C
16 284 30 8 13 A
17 284 6 12 13 A
18 95 11 0 189 w
19 143 24 112 5 r
Type: Heterodimer
Binding TFs: GCM2_TF1 (GCM motif protein)
SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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