DNA Binding Motif

						

			
Accessions: 6t78_AB (3D-footprint 20231221)

			
Names: Transcription factor SOX-11
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of human Sox11 transcription factor in complex with a short DNA fragment
Length: 12
Consensus: ACAATAAATTGT
Weblogo: 
PSSM: P0      A      C      G      T
01     89      0      7      0      A
02      6     76      6      8      C
03     96      0      0      0      A
04     70     12      6      8      A
05      0      0      0     96      T
06     96      0      0      0      A
07     96      0      0      0      A
08     89      1      6      0      A
09      6      7      0     83      T
10      0      0      0     96      T
11      6     14     70      6      G
12      0      0      0     96      T
Type: Heterodimer
Binding TFs: 6t78_A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
6t78_B (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: 6t78_C
6t78_D
			
Publications: Dodonova SO, Zhu F, Dienemann C, Taipale J, Cramer P. Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature 580:669-672 (2020). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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