DNA Binding Motif

						

			
Accessions: 3d71_A (3D-footprint 20231221)

			
Names: Multidrug-efflux transporter 1 regulator
Organisms: Bacillus subtilis, strain 168
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of E253Q BMRR bound to 22 base pair promoter site
Length: 4
Consensus: CCCT
Weblogo: 
PSSM: P0      A      C      G      T
01      9     67     11      9      C
02      9     69      9      9      C
03      9     67     11      9      C
04      0      0      0     96      T
Binding TFs: 3d71_A (MerR family regulatory protein, GyrI-like small molecule binding domain, MerR HTH family regulatory protein)
Binding Sites: 3d71_M
			
Publications: Newberry K.J, Huffman J.L, Miller M.C, Vazquez-Laslop N, Neyfakh A.A, Brennan R.G. Structures of BmrR-drug complexes reveal a rigid multidrug binding pocket and transcription activation through tyrosine expulsion. The Journal of biological chemistry 283:26795-804 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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