DNA Binding Motif

						

			
Accessions: CUX1_FOXO6 (HumanTF2 1.0)

			
Names: CUX1_FOXO6
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: rtmaaCaaahtrATCrATa
Weblogo: 
PSSM: P0      A      C      G      T
01    131     19    175     32      r
02    121    122     28    306      t
03    306    152     19     61      m
04    306    101     15     41      a
05    306     37     45    115      a
06     21    306     11     78      C
07    306     44     47     55      a
08    121     55     74     56      a
09    110     58     62     76      a
10     77     85     61     83      h
11     73     34     44    155      t
12     96     21    131     59      r
13    306      4     13     14      A
14      0      3      2    306      T
15     12    306      0     43      C
16    119     19    187      6      r
17    306      1      0     17      A
18     28      5      0    306      T
19     98     66     75     66      a
Type: Heterodimer
Binding TFs: CUX1_TF1 (Homeobox domain, CUT domain, Homeobox KN domain)
FOXO6_TF2 (Fork head domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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